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Literature summary for 1.2.4.4 extracted from
- Dissociation of branched-chain alpha-keto acid dehydrogenase kinase (BDK) from branched-chain alpha-keto acid dehydrogenase complex (BCKDC) by BDK inhibitors (2005), J. Nutr. Sci. Vitaminol., 51, 48-50.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| alpha-Chloroisocaproate | activates through release of branched-chain alpha-keto acid dehydrogenase kinase from the BCKD complex | Rattus norvegicus |  |
| alpha-Ketoisocaproate | activates through release of branched-chain alpha-keto acid dehydrogenase kinase from the BCKD complex | Rattus norvegicus | |
| alpha-ketoisovalerate | activates through release of branched-chain alpha-keto acid dehydrogenase kinase from the BCKD complex | Rattus norvegicus | |
| additional information | clofibric acid and thiamine diphosphate have no effect on the protein-protein interaction between branched-chain alpha-keto acid dehydrogenase kinase and BCKD complex | Rattus norvegicus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Rattus norvegicus | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| BCKDC | - |
Rattus norvegicus |
| branched-chain alpha-keto acid dehydrogenase complex | - |
Rattus norvegicus |
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