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Literature summary for 1.21.1.1 extracted from

  • Gaupale, T.; Mathi, A.; Ravikumar, A.; Bhargava, S.
    Localization and enzyme activity of iodotyrosine dehalogenase 1 during metamorphosis of frog Microhyla ornata (2009), Ann. N. Y. Acad. Sci., 1163, 402-406.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Microhyla ornata
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain during metamorphosis, DEHAL1 enzyme activity is higher on diiodotyrosine as compared to monoiodotyrosine. Using diiodotyrosine as a substrate, maximal activity is detected at stage 44 in the brain, while it is higher at stage 42 in the tail. With monoiodotyrosine as a substrate, highest activity is detected in the brain at stage 42 Microhyla ornata
-
cerebellum
-
Microhyla ornata
-
infundibular nucleus ventral part Microhyla ornata
-
jaw
-
Microhyla ornata
-
mucous gland
-
Microhyla ornata
-
olfactory epithelium
-
Microhyla ornata
-
pituitary gland
-
Microhyla ornata
-
tadpole tadpole tail fin. During metamorphosis, DEHAL1 enzyme activity is higher on diiodotyrosine as compared to monoiodotyrosine. Using diiodotyrosine as a substrate, maximal activity is detected at stage 44 in the brain, while it is higher at stage 42 in the tail (138.5 U/mg protein). With monoiodotyrosine as a substrate, highest activity is detected in the brain at stage 42 Microhyla ornata
-
ventricular zone ventricular lining of the fourth ventricle Microhyla ornata
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
4
-
stage 42, tail Microhyla ornata
6.1
-
stage 44, lower jaw Microhyla ornata
6.6
-
stage 46, lower jaw Microhyla ornata
9.2
-
stage 44, brain Microhyla ornata
17.9
-
stage 42, lower jaw Microhyla ornata
24.01
-
stage 44, lower jaw Microhyla ornata
28.4
-
stage 46, lower jaw Microhyla ornata
65.8
-
stage 42, brain Microhyla ornata
109
-
stage 42, brain Microhyla ornata
118.6
-
stage 44, tail Microhyla ornata
125
-
stage 46, brain Microhyla ornata
138.5
-
stage 42, tail Microhyla ornata
157.7
-
stage 44, brain Microhyla ornata

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3,5-diiodo-L-tyrosine + NADPH + H+
-
Microhyla ornata 3-iodo-L-tyrosine + NADP+ + I-
-
?
3-iodo-L-tyrosine + NADPH + H+
-
Microhyla ornata L-tyrosine + NADP+ + I-
-
?

Synonyms

Synonyms Comment Organism
DEHAL1
-
Microhyla ornata