Inhibitors | Comment | Organism | Structure |
---|---|---|---|
aurothioglucose | noncompetitive | Rattus norvegicus | |
bromoacetyl-triiodothyronine | - |
Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Rattus norvegicus | - |
- |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
31000 | - |
x * 31000, SDS-PAGE | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
comparison with hepatic 5'-deiodinase EC 1.97.1.10 | - |
Posttranslational Modification | Comment | Organism |
---|---|---|
additional information | enzyme is not a selenoprotein | Rattus norvegicus |
Purification (Comment) | Organism |
---|---|
- |
Rattus norvegicus |
Renatured (Comment) | Organism |
---|---|
delipidation of microsomes during purification results in loss of enzyme activity. Full recovering of activity is achieved by recombining phospholipids and protein, partial recovery may be achieved by addition of exogenous phospholipids to protein | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
additional information | no enzymic activity in testes and spleen | Rattus norvegicus | - |
placenta | - |
Rattus norvegicus | - |
Subunits | Comment | Organism |
---|---|---|
? | x * 31000, SDS-PAGE | Rattus norvegicus |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.43 | - |
pH 7.4, 37°C | Rattus norvegicus | aurothioglucose |