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Literature summary for 1.3.1.24 extracted from

  • Zhang, M.; Xin, W.; Yi, Z.; Li, Y.; Liu, Y.; Zhang, H.; Chen, H.; Chen, X.; Tan, S.; Zhu, D.
    Human biliverdin reductase regulates the molecular mechanism underlying cancer development (2018), J. Cell. Biochem., 119, 1337-1345 .
    View publication on PubMed

Application

Application Comment Organism
diagnostics antiapoptotic effect of the enzyme in cancers portens strategies for developing novel biomarkers and effective treatment ways for cancer patients Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P53004
-
-

Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
bilirubin + NADP+
-
Homo sapiens biliverdin + NADPH + H+
-
?

Expression

Organism Comment Expression
Homo sapiens expression is up-regulated in breast, lung, and liver cancers, but not ovarian cancer up

General Information

General Information Comment Organism
physiological function the enzyme regulates the molecular mechanism underlying cancer development Homo sapiens