Inhibitors | Comment | Organism | Structure |
---|---|---|---|
17beta-hydroxy-5alpha-androstan-3-one | 0.01 mM, 57% inhibition | Pelophylax lessonae | |
17beta-hydroxy-5beta-androstan-3-one | 0.01 mM, 28% inhibition | Pelophylax lessonae | |
androstenedione | 0.01 mM, 93% inhibition | Pelophylax lessonae | |
Cu2+ | 0.5 mM 66% inhibition | Pelophylax lessonae | |
estradiol-17beta | 0.01 mM, 29% inhibition | Pelophylax lessonae | |
estrone | 0.01 mM, 29% inhibition | Pelophylax lessonae | |
Hg2+ | 0.1 mM, 92% inhibition | Pelophylax lessonae | |
p-chloromercuribenzoate | 0.1 mM, 95% inhibition | Pelophylax lessonae | |
progesterone | 0.002 mM, 84% inhibition | Pelophylax lessonae |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0016 | - |
testosterone | - |
Pelophylax lessonae | |
0.0052 | - |
NADPH | - |
Pelophylax lessonae |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Pelophylax lessonae | 5829 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Pelophylax lessonae | - |
- |
- |
Purification (Comment) | Organism |
---|---|
partial | Pelophylax lessonae |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
forelimb muscle | male | Pelophylax lessonae | - |
skeletal muscle | - |
Pelophylax lessonae | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.0000036 | - |
testosterone reduction, enzyme activity in forelimb muscle | Pelophylax lessonae |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
17beta-hydroxyandrost-4-en-3-one + NADPH | trivial name testosterone | Pelophylax lessonae | 17beta-hydroxy-5beta-androstan-3-one + NADP+ | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
- |
Pelophylax lessonae |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6 | - |
- |
Pelophylax lessonae |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | absolutely required | Pelophylax lessonae |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00024 | - |
progesterone | - |
Pelophylax lessonae |