Literature summary for 1.3.1.38 extracted from

Poletto, S.S.; da Fonseca, I.O.; de Carvalho, L.P.; Basso, L.A.; Santos, D.S.
Selection of an Escherichia coli host that expresses mutant forms of Mycobacterium tuberculosis 2-trans enoyl-ACP(CoA) reductase and 3-ketoacyl-ACP(CoA) reductase enzymes (2004), Protein Expr. Purif., 34, 118-125.

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Protein Variants

Protein Variants	Comment	Organism
K165A	normal expression in Escherichia coli	Mycobacterium tuberculosis
K165Q	normal expression in Escherichia coli	Mycobacterium tuberculosis
Y158F	expression in Escherichia coli sub-population BL21(DE3)NH	Mycobacterium tuberculosis

Organism

Organism	UniProt	Comment	Textmining
Mycobacterium tuberculosis	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
acyl-CoA + NADP+	-	Mycobacterium tuberculosis	trans-2,3-dehydroacyl-CoA + NADPH	-	?

Synonyms

Synonyms	Comment	Organism
2-trans enoyl-ACP(CoA) reductase	-	Mycobacterium tuberculosis
InhA	-	Mycobacterium tuberculosis

Cofactor

Cofactor	Comment	Organism	Structure
NADP+	-	Mycobacterium tuberculosis

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Release 2023.1 (January 2023)