Inhibitors | Comment | Organism | Structure |
---|---|---|---|
diacetyl | - |
Mycolicibacterium smegmatis | |
additional information | substrates with chain-length higher than C16, concentration above 0.05 mM | Mycolicibacterium smegmatis | |
NAD+ | competitive to NADH | Mycolicibacterium smegmatis | |
Phenylglyoxal | - |
Mycolicibacterium smegmatis |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.021 | - |
NADH | - |
Mycolicibacterium smegmatis | |
0.0295 | - |
hexadecenoyl-CoA | - |
Mycolicibacterium smegmatis | |
0.0558 | - |
dodec-2-enoyl-CoA | - |
Mycolicibacterium smegmatis | |
0.0893 | - |
2-decenoyl-CoA | - |
Mycolicibacterium smegmatis | |
0.2327 | - |
(2E)-oct-2-enoyl-CoA | - |
Mycolicibacterium smegmatis |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
26000 | - |
? * 26000, SDS-PAGE | Mycolicibacterium smegmatis |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
acyl-CoA + NAD+ | Mycolicibacterium smegmatis | fatty acid elongation | trans-2,3-didehydroacyl-CoA + NADH | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mycolicibacterium smegmatis | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Mycolicibacterium smegmatis |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
17.54 | - |
- |
Mycolicibacterium smegmatis |
Storage Stability | Organism |
---|---|
-20°C, several months | Mycolicibacterium smegmatis |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-decenoyl-CoA + NADH + H+ | - |
Mycolicibacterium smegmatis | decanoyl-CoA + NAD+ | - |
r | |
2-hexadecenoyl-CoA + NADH + H+ | - |
Mycolicibacterium smegmatis | hexadecanoyl-CoA + NAD+ | - |
r | |
acyl-CoA + NAD+ | fatty acid elongation | Mycolicibacterium smegmatis | trans-2,3-didehydroacyl-CoA + NADH | - |
? | |
dodec-2-enoyl-CoA + NADH + H+ | - |
Mycolicibacterium smegmatis | dodecanoyl-CoA + NAD+ | - |
r | |
additional information | inert to substrates with chain length below C8 | Mycolicibacterium smegmatis | ? | - |
? | |
trans-2-decenoyl-CoA + NADH | - |
Mycolicibacterium smegmatis | decanoyl-CoA + NAD+ | - |
? | |
trans-2-dodecenoyl-CoA + NADH | - |
Mycolicibacterium smegmatis | dodecanoyl-CoA + NAD+ | i.e. laurate | ? | |
trans-2-hexadecenoyl-CoA + NADH | - |
Mycolicibacterium smegmatis | hexadecanoyl-CoA + NAD+ | - |
? | |
trans-2-octenoyl-CoA + NADH | - |
Mycolicibacterium smegmatis | octanoyl-CoA + NAD+ | - |
? |
Subunits | Comment | Organism |
---|---|---|
oligomer | ? * 26000, SDS-PAGE | Mycolicibacterium smegmatis |
Synonyms | Comment | Organism |
---|---|---|
2-enoyl-reductase | - |
Mycolicibacterium smegmatis |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
5 | 5.5 | - |
Mycolicibacterium smegmatis |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADH | sole electron donor | Mycolicibacterium smegmatis |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.047 | - |
NAD+ | - |
Mycolicibacterium smegmatis |