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Literature summary for 1.3.1.44 extracted from
- Crystallization and preliminary X-ray crystallographic studies of enoyl-acyl carrier protein reductase (FabI) from Pseudomonas aeruginosa (2011), Acta Crystallogr. Sect. F, 67, 214-216.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in Escherichia coli | Pseudomonas aeruginosa |
Crystallization (Commentary)
| Crystallization (Comment) | Organism |
|---|---|
| purified and crystallized as an apoenzyme and in a complex form with NADH and triclosan. The crystals of native and complexed FabI diffract to resolutions of 2.6 and 1.8 A, respectively. The crystals both belong to space group P2-1, with unit-cell parameters a = 117.32, b = 155.844, c = 129.448 A , beta = 111.061° for the native enzyme and a = 64.784, b = 107.573, c = 73.517 A, beta = 116.162° for the complex | Pseudomonas aeruginosa |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| triclosan | - |
Pseudomonas aeruginosa |  |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 28000 | - |
SDS-PAGE | Pseudomonas aeruginosa |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Pseudomonas aeruginosa | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| purified by gel-filtration chromatography on a HiLoad 16/60 superdex 200 column | Pseudomonas aeruginosa |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| enoyl-acyl carrier protein reductase | - |
Pseudomonas aeruginosa |
| FabI | - |
Pseudomonas aeruginosa |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NADH | - |
Pseudomonas aeruginosa | |
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Release 2023.1 (January 2023)
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