General Stability | Organism |
---|---|
fatty acid synthetase with enoyl-CoA reductase activity: denaturation by mechanical agitation, exposure to air, uneven surfaces such as scratched glass, membranes for ultrafiltration | Bos taurus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
butyryl-CoA | - |
Bos taurus | |
NADP+ | - |
Bos taurus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Oxidation Stability | Organism |
---|---|
denaturation by exposure to air | Bos taurus |
Purification (Comment) | Organism |
---|---|
fatty acid synthetase, also exhibiting crotonyl-CoA reductase activity | Bos taurus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
mammary gland | - |
Bos taurus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
1 | - |
- |
Bos taurus |
Storage Stability | Organism |
---|---|
liquid N2, 30-50% loss of activity by thawing | Bos taurus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-methyl-trans-crotonyl-CoA + NADPH | 2% of trans-crotonyl-CoA activity | Bos taurus | 2-methylbutanoyl-CoA + NADP+ | - |
? | |
2-trans-dodecenoyl-CoA + NAD(P)H | 15% of trans-crotonyl-CoA activity | Bos taurus | dodecanoyl-CoA + NAD(P)+ | - |
? | |
2-trans-hexadecenoyl-CoA + NADPH | 13% of trans-crotonyl-CoA activity | Bos taurus | hexadecanoyl CoA + NADP+ | - |
? | |
2-trans-hexenoyl-CoA + NAD(P)H | 30% of trans-crotonyl-CoA activity | Bos taurus | hexanoyl-CoA + NADP+ | - |
? | |
3-butenoyl-CoA + NADPH | 7% of trans-crotonyl-CoA activity | Bos taurus | butanoyl-CoA + NADP+ | - |
? | |
3-methyl-crotonyl-CoA + NADPH | 17% of trans-crotonyl-CoA activity | Bos taurus | 3-methylbutanoyl-CoA + NADP+ | - |
? | |
crotonyl-CoA + NAD(P)H | cis-crotonyl-CoA 30% of trans-crotonyl-CoA activity | Bos taurus | butanoyl-CoA + NADP+ | - |
? | |
additional information | no reduction of trans-crotonyl-S-pantetheine | Bos taurus | ? | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | inactive with NADH | Bos taurus |