KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0005 | - |
2-trans-octenoyl-CoA | reductase type I | Candida albicans | |
0.0011 | - |
2-cis-octenoyl-CoA | reductase type I | Candida albicans | |
0.0025 | - |
5-hydroxyundec-cis-2-enoyl-CoA | reductase type I | Candida albicans | |
0.003 | - |
5-hydroxyundec-cis-2-enoyl-CoA | reductase type II | Candida albicans | |
0.01 | - |
2-trans-octenoyl-CoA | reductase type II | Candida albicans | |
0.053 | - |
2-cis-octenoyl-CoA | reductase type II | Candida albicans |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
85000 | - |
reductase type II, gel filtration | Candida albicans |
180000 | - |
reductase type I, gel filtration | Candida albicans |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
5-hydroxyundec-cis-2-enoyl-CoA + NADPH | Candida albicans | - |
5-hydroxyundecanoyl-CoA + NADP+ | - |
? | |
additional information | Candida albicans | role in beta-oxidation of fatty acids | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Candida albicans | - |
reductase type I and II | - |
Purification (Comment) | Organism |
---|---|
reductase type I and II | Candida albicans |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
- |
Candida albicans |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-cis-octenoyl-CoA + NADPH | - |
Candida albicans | octanoyl-CoA + NADP+ | - |
? | |
2-trans-octenoyl-CoA + NAD(P)H | - |
Candida albicans | octanoyl-CoA + NADP+ | - |
? | |
5-hydroxyundec-cis-2-enoyl-CoA + NADPH | - |
Candida albicans | 5-hydroxyundecanoyl-CoA + NADP+ | - |
? | |
additional information | role in beta-oxidation of fatty acids | Candida albicans | ? | - |
? |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
50 | - |
reductase type I: 30 min, 50% loss of activity, reductase type II: no activity with 5 hydroxyundec-cis-2-enoyl-CoA, up to 80% activity with cis or trans-oct-2-enoyl-CoA | Candida albicans |
60 | - |
reductase type I: 3 min, 80% loss of activity | Candida albicans |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6.5 | 8.5 | depending on substrate and type of reductase | Candida albicans |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | inactive with NADH | Candida albicans |