Inhibitors | Comment | Organism | Structure |
---|---|---|---|
4-acetoxyanthecotulide | moderate inhibition | Plasmodium falciparum | |
4-hydroxyanthecotulide | moderate inhibition | Plasmodium falciparum | |
anthecotulide | - |
Mycobacterium tuberculosis | |
anthecotulide | moderate inhibition | Plasmodium falciparum | |
additional information | not inhibited by anthecotulide, 4-hydroxyanthecotulide, and 4-acetoxyanthecotulide | Escherichia coli | |
additional information | not inhibited by 4-hydroxyanthecotulide and 4-acetoxyanthecotulide | Mycobacterium tuberculosis |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
strain ATCC 35218 | - |
Mycobacterium tuberculosis | - |
- |
- |
Mycobacterium tuberculosis H37Rv | - |
- |
- |
Plasmodium falciparum | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
crotonyl-CoA + NADH + H+ | - |
Escherichia coli | butyryl-CoA + NAD+ | - |
? | |
crotonyl-CoA + NADH + H+ | - |
Mycobacterium tuberculosis | butyryl-CoA + NAD+ | - |
? | |
crotonyl-CoA + NADH + H+ | - |
Plasmodium falciparum | butyryl-CoA + NAD+ | - |
? | |
crotonyl-CoA + NADH + H+ | - |
Mycobacterium tuberculosis H37Rv | butyryl-CoA + NAD+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
enoyl-ACP reductase | - |
Escherichia coli |
enoyl-ACP reductase | - |
Mycobacterium tuberculosis |
enoyl-ACP reductase | - |
Plasmodium falciparum |
FabI | - |
Escherichia coli |
FabI | - |
Mycobacterium tuberculosis |
FabI | - |
Plasmodium falciparum |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADH | - |
Escherichia coli | |
NADH | - |
Mycobacterium tuberculosis | |
NADH | - |
Plasmodium falciparum |