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Literature summary for 1.3.1.9 extracted from

  • Kwon, Y.J.; Sohn, M.J.; Oh, T.; Cho, S.N.; Kim, C.J.; Kim, W.G.
    Panosialins, inhibitors of enoyl-ACP reductase from Streptomyces sp. AN1761 (2013), J. Microbiol. Biotechnol., 23, 184-188.
    View publication on PubMed
Search for more literature for 1.3.1.9

Inhibitors

Inhibitors Comment Organism Structure
panosialin A acylbenzenediol sulfate metabolites from Streptomyces sp. AN1761, potently inhibits bacterial enoyl-ACP reductases of Staphylococcus aureus, Streptococcus pneumoniae, and Mycobacterium tuberculosis Mycobacterium tuberculosis
panosialin A acylbenzenediol sulfate metabolites from Streptomyces sp. AN1761, potently inhibits bacterial enoyl-ACP reductases of Staphylococcus aureus, Streptococcus pneumoniae, and Mycobacterium tuberculosis Streptococcus pneumoniae
panosialin B acylbenzenediol sulfate metabolites from Streptomyces sp. AN1761, potently inhibits bacterial enoyl-ACP reductases of Staphylococcus aureus, Streptococcus pneumoniae, and Mycobacterium tuberculosis Mycobacterium tuberculosis
panosialin B acylbenzenediol sulfate metabolites from Streptomyces sp. AN1761, potently inhibits bacterial enoyl-ACP reductases of Staphylococcus aureus, Streptococcus pneumoniae, and Mycobacterium tuberculosis Streptococcus pneumoniae
panosialin wA acylbenzenediol sulfate metabolites from Streptomyces sp. AN1761, potently inhibits bacterial enoyl-ACP reductases of Staphylococcus aureus, Streptococcus pneumoniae, and Mycobacterium tuberculosis Mycobacterium tuberculosis
panosialin wA acylbenzenediol sulfate metabolites from Streptomyces sp. AN1761, potently inhibits bacterial enoyl-ACP reductases of Staphylococcus aureus, Streptococcus pneumoniae, and Mycobacterium tuberculosis Streptococcus pneumoniae
panosialin wB acylbenzenediol sulfate metabolites from Streptomyces sp. AN1761, potently inhibits bacterial enoyl-ACP reductases of Staphylococcus aureus, Streptococcus pneumoniae, and Mycobacterium tuberculosis Mycobacterium tuberculosis
panosialin wB acylbenzenediol sulfate metabolites from Streptomyces sp. AN1761, potently inhibits bacterial enoyl-ACP reductases of Staphylococcus aureus, Streptococcus pneumoniae, and Mycobacterium tuberculosis Streptococcus pneumoniae

Organism

Organism UniProt Comment Textmining
Mycobacterium tuberculosis
-
-
-
Streptococcus pneumoniae
-
-
-

Synonyms

Synonyms Comment Organism
FabI
-
 Streptococcus pneumoniae
InhA
-
 Mycobacterium tuberculosis

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.0039
-
 pH 6.5, temperature not specified in the publication Streptococcus pneumoniae panosialin A
0.0052
-
 pH 6.5, temperature not specified in the publication Streptococcus pneumoniae panosialin B
0.0052
-
 pH 6.5, temperature not specified in the publication Streptococcus pneumoniae panosialin wA
0.0055
-
 pH 6.5, temperature not specified in the publication Streptococcus pneumoniae panosialin wB
0.0085
-
 pH 8.0, temperature not specified in the publication Mycobacterium tuberculosis panosialin B
0.0091
-
 pH 8.0, temperature not specified in the publication Mycobacterium tuberculosis panosialin wB
0.0096
-
 pH 8.0, temperature not specified in the publication Mycobacterium tuberculosis panosialin wA
0.0118
-
 pH 8.0, temperature not specified in the publication Mycobacterium tuberculosis panosialin A