Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.3.3.3 extracted from

  • Tait, G.H.
    Coproporphyrinogenase activities in extracts of Rhodopseudomonas spheroids (1976), Biochem. J., 118, 28P-29P.
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
1,10-phenanthroline 90% inhibition of anaerobic reaction at 0.17 mM Cereibacter sphaeroides
2,2-bipyridyl 77% inhibition of anaerobic reaction at 1.5 mM Cereibacter sphaeroides
2,4-dinitrophenol 90% inhibition of anaerobic reaction at 0.7 mM Cereibacter sphaeroides
FAD 95% inhibition of anaerobic reaction at 0.03 mM Cereibacter sphaeroides
FMN 95% inhibition of anaerobic reaction at 0.03 mM Cereibacter sphaeroides
riboflavin 95% inhibition of anaerobic reaction at 0.03 mM Cereibacter sphaeroides

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
coproporphyrinogen-III + 2 NADP+ Cereibacter sphaeroides oxidation under anaerobic conditions strictly requires NADP+ as electron acceptor protoporphyrinogen-IX + 2 CO2 + 2 NADPH + 2 H+
-
?
coproporphyrinogen-III + ? Cereibacter sphaeroides anaerobic enzyme, presence of Mg2+, L-Met, ATP, NADH and NADP+ protoporphyrinogen-IX + ?
-
?
coproporphyrinogen-III + O2 + 2 H+ Cereibacter sphaeroides
-
protoporphyrinogen-IX + 2 CO2 + 2 H2O
-
?

Organism

Organism UniProt Comment Textmining
Cereibacter sphaeroides
-
-
-

Oxidation Stability

Oxidation Stability Organism
succinate protects against oxidation Cereibacter sphaeroides

Source Tissue

Source Tissue Comment Organism Textmining
cell culture
-
Cereibacter sphaeroides
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
coproporphyrinogen-III + 2 NADP+ oxidation under anaerobic conditions strictly requires NADP+ as electron acceptor Cereibacter sphaeroides protoporphyrinogen-IX + 2 CO2 + 2 NADPH + 2 H+
-
?
coproporphyrinogen-III + ? anaerobic enzyme, presence of Mg2+, L-Met, ATP, NADH and NADP+ Cereibacter sphaeroides protoporphyrinogen-IX + ?
-
?
coproporphyrinogen-III + O2 + 2 H+
-
Cereibacter sphaeroides protoporphyrinogen-IX + 2 CO2 + 2 H2O
-
?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7
-
aerobic reaction Cereibacter sphaeroides
8.5
-
anaerobic reaction Cereibacter sphaeroides

Cofactor

Cofactor Comment Organism Structure
ATP strictly required for anaerobic enzyme Cereibacter sphaeroides
NAD+ only anaerobic enzyme, slightly less active than NADP+ Cereibacter sphaeroides
NADP+ only anaerobic enzyme, maximum activity together with NADH Cereibacter sphaeroides