Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1,10-phenanthroline | 90% inhibition of anaerobic reaction at 0.17 mM | Cereibacter sphaeroides | |
2,2-bipyridyl | 77% inhibition of anaerobic reaction at 1.5 mM | Cereibacter sphaeroides | |
2,4-dinitrophenol | 90% inhibition of anaerobic reaction at 0.7 mM | Cereibacter sphaeroides | |
FAD | 95% inhibition of anaerobic reaction at 0.03 mM | Cereibacter sphaeroides | |
FMN | 95% inhibition of anaerobic reaction at 0.03 mM | Cereibacter sphaeroides | |
riboflavin | 95% inhibition of anaerobic reaction at 0.03 mM | Cereibacter sphaeroides |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
coproporphyrinogen-III + 2 NADP+ | Cereibacter sphaeroides | oxidation under anaerobic conditions strictly requires NADP+ as electron acceptor | protoporphyrinogen-IX + 2 CO2 + 2 NADPH + 2 H+ | - |
? | |
coproporphyrinogen-III + ? | Cereibacter sphaeroides | anaerobic enzyme, presence of Mg2+, L-Met, ATP, NADH and NADP+ | protoporphyrinogen-IX + ? | - |
? | |
coproporphyrinogen-III + O2 + 2 H+ | Cereibacter sphaeroides | - |
protoporphyrinogen-IX + 2 CO2 + 2 H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Cereibacter sphaeroides | - |
- |
- |
Oxidation Stability | Organism |
---|---|
succinate protects against oxidation | Cereibacter sphaeroides |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
cell culture | - |
Cereibacter sphaeroides | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
coproporphyrinogen-III + 2 NADP+ | oxidation under anaerobic conditions strictly requires NADP+ as electron acceptor | Cereibacter sphaeroides | protoporphyrinogen-IX + 2 CO2 + 2 NADPH + 2 H+ | - |
? | |
coproporphyrinogen-III + ? | anaerobic enzyme, presence of Mg2+, L-Met, ATP, NADH and NADP+ | Cereibacter sphaeroides | protoporphyrinogen-IX + ? | - |
? | |
coproporphyrinogen-III + O2 + 2 H+ | - |
Cereibacter sphaeroides | protoporphyrinogen-IX + 2 CO2 + 2 H2O | - |
? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7 | - |
aerobic reaction | Cereibacter sphaeroides |
8.5 | - |
anaerobic reaction | Cereibacter sphaeroides |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | strictly required for anaerobic enzyme | Cereibacter sphaeroides | |
NAD+ | only anaerobic enzyme, slightly less active than NADP+ | Cereibacter sphaeroides | |
NADP+ | only anaerobic enzyme, maximum activity together with NADH | Cereibacter sphaeroides |