Application | Comment | Organism |
---|---|---|
medicine | increase of severity of porphyrias with monovinyl accumulation, ability of the increased levels of C-IV to compete with the authentic substrate has important implications for clinical porphyrias | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli BL21(DE3)RIL | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00013 | - |
Coproporphyrinogen-III | with monovinyl product | Homo sapiens | |
0.00065 | - |
coproporphyrinogen-IV | with monovinyl product | Homo sapiens | |
0.00068 | - |
Coproporphyrinogen-III | total product | Homo sapiens | |
0.0007 | - |
Coproporphyrinogen-III | with divinyl product | Homo sapiens | |
0.00078 | - |
coproporphyrinogen-IV | total product | Homo sapiens | |
0.00083 | - |
coproporphyrinogen-IV | with divinyl product | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
37700 | - |
37700, SDS-PAGE | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
Ni2+ affinity chromatography | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
coproporphyrinogen-III + O2 + 2 H+ | small amount of the monovinyl intermediate | Homo sapiens | protoporphyrinogen-IX + 2 CO2 + 2 H2O | - |
? | |
coproporphyrinogen-IV + O2 | monovinyl intermediate that accumulates before being converted to an isomer | Homo sapiens | protoporphyrinogen-XIII + 2 CO2 + 2 H2O | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | 37700, SDS-PAGE | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
copro'gen oxidase | - |
Homo sapiens |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0033 | - |
Coproporphyrinogen-III | with monovinyl product | Homo sapiens | |
0.01167 | - |
coproporphyrinogen-IV | with divinyl product | Homo sapiens | |
0.0283 | - |
coproporphyrinogen-IV | with monovinyl product | Homo sapiens | |
0.043 | - |
coproporphyrinogen-IV | total product | Homo sapiens | |
0.055 | - |
Coproporphyrinogen-III | with divinyl product | Homo sapiens | |
0.06 | - |
Coproporphyrinogen-III | total product | Homo sapiens |