Literature summary for 1.3.8.1 extracted from

Fendrich, G.; Abeles, R.H.
Mechanism of action of butyryl-CoA dehydrogenase: reactions with acetylenic, olefinic, and fluorinated substrate analogues (1982), Biochemistry, 21, 6685-6695.

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Inhibitors

Inhibitors	Comment	Organism	Structure
3-Chloro-3-butenoylpantetheine	-	Megasphaera elsdenii
3-Pentenoylpantetheine	0.31 mM, complete loss of activity after 40 s	Megasphaera elsdenii

Organism

Organism	UniProt	Comment	Textmining
Megasphaera elsdenii	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
(3,3-difluorobutyryl)pantetheine + phenazine methosulfate + dichlorophenolindophenol	-	Megasphaera elsdenii	3-fluoro-2-butenoylpantetheine + HF	-	?
2-propenoyl-CoA + reduced electron transfer flavoprotein	-	Megasphaera elsdenii	propanoyl-CoA + electron transfer protein	-	?
3-fluoropropionyl-CoA + phenazine methosulfate + dichlorophenolindophenol	-	Megasphaera elsdenii	2-propenoyl-CoA + HF	-	?

Turnover Number [1/s]

Turnover Number Minimum [1/s]	Turnover Number Maximum [1/s]	Substrate	Comment	Organism	Structure
0.0333	-	propionyl-CoA	-	Megasphaera elsdenii

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Release 2023.1 (January 2023)