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Literature summary for 1.3.8.2 extracted from

  • Maeda, I.
    Genetic modification in Bacillus subtilis for production of C30 carotenoids (2012), Methods Mol. Biol., 892, 197-205.
    View publication on PubMed
Search for more literature for 1.3.8.2

Cloned(Commentary)

Cloned (Comment) Organism
coexpression with dehydroqualene desarurase with dehydrosqualene synthase and induction of endogenous genes crtP and crtQ encoding mixed function oxidase and glycosyltransferase for production of glycosylated C30 carotenoic acid, overview Staphylococcus aureus
gene crtN, functional expression in Bacillus subtilis, coexpression with dehydroqualene synthase and induction of endogenous genes crtP and crtQ Staphylococcus aureus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
15-cis-4,4'-diapophytoene + 4 FAD Staphylococcus aureus
-
 all-trans-4,4'-diapolycopene + 4 FADH2
-
 ?

Organism

Organism UniProt Comment Textmining
Staphylococcus aureus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
15-cis-4,4'-diapophytoene + 4 FAD
-
 Staphylococcus aureus all-trans-4,4'-diapolycopene + 4 FADH2
-
 ?

Synonyms

Synonyms Comment Organism
CrtN
-
 Staphylococcus aureus
dehydrosqualene desaturase
-
 Staphylococcus aureus

Cofactor

Cofactor Comment Organism Structure
FAD
-
 Staphylococcus aureus

General Information

General Information Comment Organism
metabolism dehydrosqualene synthase converts farnesyl diphosphate to dehydrosqualene, dehydrosqualene desaturase then converts dehydrosqualene to the yelllow carotenoid 4,4'-diaponeurosporene Staphylococcus aureus