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Literature summary for 1.3.8.4 extracted from

  • Tajima, G.; Sakura, N.; Yofune, H.; Dwi Bahagia Febriani, A.; Nishimura, Y.; Sakamoto, A.; Ono, H.; Shigematsu, Y.; Kobayashi, M.
    Establishment of a practical enzymatic assay method for determination of isovaleryl-CoA dehydrogenase activity using high-performance liquid chromatography (2005), Clin. Chim. Acta, 353, 193-199.
    View publication on PubMed
Search for more literature for 1.3.8.4

Application

Application Comment Organism
diagnostics enzyme activity assay development for determination of isovaleric acidemia in newborn disorder screening Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
additional information
-
 additional information kinetics Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
isovaleryl-CoA + acceptor Homo sapiens
-
 3-methylcrotonyl-CoA + reduced acceptor
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
blood peripheral Homo sapiens
-
lymphocyte
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
 enzyme assay development and optimization Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
isovaleryl-CoA + acceptor
-
 Homo sapiens 3-methylcrotonyl-CoA + reduced acceptor
-
 ?
isovaleryl-CoA + phenazine methosulfate
-
 Homo sapiens 3-methylcrotonyl-CoA + reduced phenazine methosulfate
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7
-
 assay at Homo sapiens

Cofactor

Cofactor Comment Organism Structure
FAD
-
 Homo sapiens