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Literature summary for 1.4.1.1 extracted from
- Fundamental differences in bioaffinity of amino acid dehydrogenases for N6- and S6-linked immobilized cofactors using kinetic-based enzyme-capture strategies (2005), Anal. Biochem., 338, 102-112.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| D-Cys | - |
Bacillus subtilis |  |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 1.63 | - |
L-Ala | at pH 8.6 | Bacillus subtilis | |
| 1.96 | - |
L-Ala | at pH 7.4 | Bacillus subtilis | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bacillus subtilis | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-Ala + H2O + NAD+ | - |
Bacillus subtilis | pyruvate + NH3 + NADH | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| ALADH | - |
Bacillus subtilis |
| NAD+-dependent alanine dehydrogenase | - |
Bacillus subtilis |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NAD+ | affinity for NAD+ immobilized through an N6 linkage, as opposed to an N1 linkage, replacement of the nitrogen with sulfur to produce an S6 linkage | Bacillus subtilis | |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.71 | - |
D-Cys | at pH 8.6 | Bacillus subtilis | |
| 1.88 | - |
D-Cys | at pH 7.4 | Bacillus subtilis | |
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