Literature summary for 1.4.1.16 extracted from

Lam, L.K.P.; Arnold, L.D.; Kalantar, T.H.; Kelland, J.G.; Lane-Bell, P.M.; Palcic, M.M.; Pickard, M.A.; Vederas, J.C.
Analogs of diaminopimelic acid as inhibitors of meso-diaminopimelate dehydrogenase and LL-diaminopimelate epimerase (1988), J. Biol. Chem., 263, 11814-11819.

Search for more literature for 1.4.1.16

Organism

Organism	UniProt	Comment	Textmining
Lysinibacillus sphaericus	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2,6-diaminoheptanedioic acid + H2O + NADP+	mixture of all possible stereoisomers, 4% of activity with meso-2,6-diaminopimelate	Lysinibacillus sphaericus	2-amino-6-oxopimelate + NH3 + NADPH	-	r
2-amino-6-(hydroxyamino)heptanedioic acid + H2O + NADP+	mixture of all possible stereoisomers, 22% of activity with meso-2,6-diaminopimelate	Lysinibacillus sphaericus	2-hydroxyamino-6-oxopimelate + NH3 + NADPH	-	r
4-methylene diaminopimelate + H2O + NADP+	mixture of all possible stereoisomers, 4% of activity with meso-2,6-diaminopimelate	Lysinibacillus sphaericus	4-methyleneamino-6-oxopimelate + NH3 + NADPH	-	r
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H	-	Lysinibacillus sphaericus	meso-2,6-diaminoheptanedioate + H2O + NAD(P)+	-	r

Cofactor

Cofactor	Comment	Organism	Structure
NADPH	-	Lysinibacillus sphaericus

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)