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Literature summary for 1.4.1.16 extracted from

  • White, P.J.
    The essential role of diaminopimelate dehydrogenase in the biosynthesis of lysine by Bacillus sphaericus (1983), J. Gen. Microbiol., 129, 739-749.
No PubMed abstract available
Search for more literature for 1.4.1.16

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-2-amino-6-oxoheptanedioate + NH3 + NADPH Lysinibacillus sphaericus
-
 meso-2,6-diaminoheptanedioate + H2O + NADP+
-
 r

Organism

Organism UniProt Comment Textmining
Lysinibacillus sphaericus
-
-
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.237
-
 reductive amination of 2-amino-6-oxopimelate in crude extracts at pH 7.5 Lysinibacillus sphaericus
0.287
-
 oxidative deamination of meso-diaminopimelate in crude extracts at pH 10.5 Lysinibacillus sphaericus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H
-
 Lysinibacillus sphaericus meso-2,6-diaminoheptanedioate + H2O + NAD(P)+
-
 r
L-2-amino-6-oxoheptanedioate + NH3 + NADPH
-
 Lysinibacillus sphaericus meso-2,6-diaminoheptanedioate + H2O + NADP+
-
 r

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
 2-amino-6-oxopimelate + NH3 + NADPH Lysinibacillus sphaericus

Cofactor

Cofactor Comment Organism Structure
NADPH
-
 Lysinibacillus sphaericus