Crystallization (Comment) | Organism |
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hanging drop method of vapour diffusion, crystals belong to space group C2 with a hexamer in the asymmetric unit and have lattice constants a = 141.9 A, b = 197.5 A and c = 125.7 A with beta = 113.6°, the crystal structure of the extremely thermostable glutamate dehydrogenase from Thermococcus litoralis determined at 2.5 A resolution is compared to that from the hyperthermophile Pyrococcus furiosus. The less stable Thermococcus litoralis enzyme has a decreased number of ion pair interactions; modified patterns of hydrogen bonding resulting from isosteric sequence changes; substitutions that decrease packing efficiency; and substitutions which give rise to subtle but distinct shifts in both main-chain and side-chain elements of the structure | Thermococcus litoralis |
Organism | UniProt | Comment | Textmining |
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Thermococcus litoralis | Q56304 | - |
- |
Synonyms | Comment | Organism |
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GluDH | - |
Thermococcus litoralis |