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Literature summary for 1.4.1.4 extracted from

  • Rosario, C.J.; Bender, R.A.
    Importance of tetramer formation by the nitrogen assimilation control protein for strong repression of glutamate dehydrogenase formation in Klebsiella pneumoniae (2005), J. Bacteriol., 187, 8291-8299.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
additional information in order for the wild-type nitrogen assimilation control protein to exert strong repression of gdhA, it must form a tetramer that bridges the two sites at gdhA, similar to other DNA looping models, the negative control mutants of nitrogen assimilation control protein fail to tetramerize and cannot form this loop, thus fail to exert the strong repression at gdhA Klebsiella pneumoniae

Inhibitors

Inhibitors Comment Organism Structure
nitrogen assimilation control protein represses the transcription of the gene gdhA Klebsiella pneumoniae

Organism

Organism UniProt Comment Textmining
Klebsiella pneumoniae
-
-
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Klebsiella pneumoniae MK53
-
-
-

Synonyms

Synonyms Comment Organism
GdhA
-
Klebsiella pneumoniae
glutamate dehydrogenase
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Klebsiella pneumoniae