Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.4.3.13 extracted from

  • Levene, C.I.; Carrington, M.J.
    The inhibition of protein-lysine 6-oxidase by various lathyrogens. Evidence for two different mechanisms (1985), Biochem. J., 232, 293-296.
    View publication on PubMedView publication on EuropePMC

Activating Compound

Activating Compound Comment Organism Structure
pyridoxal derivative Gallus gallus

Inhibitors

Inhibitors Comment Organism Structure
beta-aminopropionitrile lathyrogen, organic nitrile group, blocks active site irreversibly and binds covalently Gallus gallus
Isonicotinic acid hydrazide lathyrogen, hydrazide group Gallus gallus
Semicarbazide lathyrogen, ureide group Gallus gallus

Metals/Ions

Metals/Ions Comment Organism Structure
Cu2+
-
Gallus gallus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
collagen + H2O + O2 Gallus gallus
-
allysyl-collagen + NH3 + H2O2
-
?
elastin + H2O + O2 Gallus gallus
-
allysyl-elastin + NH3 + H2O2
-
?

Organism

Organism UniProt Comment Textmining
Gallus gallus
-
embryo
-

Source Tissue

Source Tissue Comment Organism Textmining
aorta
-
Gallus gallus
-
bone leg Gallus gallus
-
cartilage
-
Gallus gallus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
collagen + H2O + O2
-
Gallus gallus allysyl-collagen + NH3 + H2O2
-
?
elastin + H2O + O2
-
Gallus gallus allysyl-elastin + NH3 + H2O2
-
?
peptidyl-L-hydroxylysyl-peptide + O2 + H2O
-
Gallus gallus peptidyl-L-2-amino-5-hydroxy-6-oxohexanoyl-peptide + NH3 + H2O2
-
?
peptidyl-L-lysyl-peptide + O2 + H2O
-
Gallus gallus peptidyl-L-allysyl-peptide + NH3 + H2O2
-
?