Activating Compound | Comment | Organism | Structure |
---|---|---|---|
tumor growth factor-beta1 | stabilizes LOX mRNA leading to an increase in LOX activity | Mus musculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-mercaptopyridine-N-oxide | - |
Mus musculus | |
alpha2-Macroglobulin | - |
Mus musculus | |
beta-aminopropionitrile | - |
Mus musculus | |
heparin | - |
Mus musculus | |
homocysteine thiolactone | - |
Mus musculus | |
low-density lipoprotein | down-regulates LOX expression | Mus musculus | |
taurine | - |
Mus musculus | |
tumor necrosis factor-alpha | down-regulates LOX expression | Mus musculus | |
vitamin B3 | - |
Mus musculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Mus musculus | 5829 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Cu2+ | dependent | Mus musculus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
32000 | - |
mature and catalytically active enzyme, SDS-PAGE | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
peptidyl-L-lysyl-peptide + O2 + H2O | - |
Mus musculus | peptidyl-allysyl-peptide + NH3 + H2O2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
LOX | - |
Mus musculus |
lysyl oxidase | - |
Mus musculus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
lysyl-tyrosyl-quinone | - |
Mus musculus |