Literature summary for 1.4.3.2 extracted from

Souza, D.H.F.; Eugenio, L.M.; Fletcher, J.E.; Jiang, M.S.; Garratt, R.C.; Oliva, G.; Selistre-de-Araujo, H.S.
Isolation and structural characterization of a cytotoxic L-amino acid oxidase from Agkistrodon contortrix laticinctus snake venom: Preliminary crystallographic data (1999), Arch. Biochem. Biophys., 368, 285-290.

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Crystallization (Commentary)

Crystallization (Comment)	Organism
-	Agkistrodon contortrix laticinctus

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
12000	-	gel filtration	Agkistrodon contortrix laticinctus
60000	-	2 * 60000, SDS-PAGE	Agkistrodon contortrix laticinctus

Organism

Organism	UniProt	Comment	Textmining
Agkistrodon contortrix laticinctus	-	venom	-

Purification (Commentary)

Purification (Comment)	Organism
-	Agkistrodon contortrix laticinctus

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
159	-	L-alanine	Agkistrodon contortrix laticinctus
272	-	L-histidine	Agkistrodon contortrix laticinctus
282	-	L-tryptophan	Agkistrodon contortrix laticinctus
564	-	L-leucine	Agkistrodon contortrix laticinctus
590	-	L-arginine	Agkistrodon contortrix laticinctus
751	-	L-valine	Agkistrodon contortrix laticinctus
772	-	L-methionine	Agkistrodon contortrix laticinctus
776	-	L-phenylalanine	Agkistrodon contortrix laticinctus
868	-	L-isoleucine	Agkistrodon contortrix laticinctus

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
L-amino acid + H2O + O2	-	Agkistrodon contortrix laticinctus	2-oxo acid + NH3 + H2O2	-	?
L-leucine + H2O + O2	no reaction with D-leucine	Agkistrodon contortrix laticinctus	4-methyl-2-oxopentanoic acid + NH3 + H2O2	-	?
additional information	shows apoptosis-inducing activity in cell cultures	Agkistrodon contortrix laticinctus	?	-	?

Subunits

Subunits	Comment	Organism
dimer	2 * 60000, SDS-PAGE	Agkistrodon contortrix laticinctus

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Release 2023.1 (January 2023)