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Literature summary for 1.4.3.2 extracted from

  • Ciscotto, P.; Machado de Avila, R.A.; Coelho, E.A.; Oliveira, J.; Diniz, C.G.; Farias, L.M.; de Carvalho, M.A.; Maria, W.S.; Sanchez, E.F.; Borges, A.; Chavez-Olortegui, C.
    Antigenic, microbicidal and antiparasitic properties of an L-amino acid oxidase isolated from Bothrops jararaca snake venom (2009), Toxicon, 53, 330-341.
    View publication on PubMed
Search for more literature for 1.4.3.2

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular venom Bothrops jararaca
-
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
38200
-
 x * 38200, deglycosylated enzyme, SDS-PAGE Bothrops jararaca

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Bothrops jararaca the venom enzyme from Bothrops jararaca show high antibacterial activity, e.g. against Staphylococcus aureus, via the produced H2O2, overview. The enzyme also shows hemolytic and leishmanicidal activity, overview ?
-
 ?

Organism

Organism UniProt Comment Textmining
Bothrops jararaca
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
flavoprotein
-
 Bothrops jararaca
glycoprotein
-
 Bothrops jararaca

Purification (Commentary)

Purification (Comment) Organism
native enzyme from venom by gel filtration, anion exchange and heparin affinity chromatography Bothrops jararaca

Source Tissue

Source Tissue Comment Organism Textmining
venom
-
 Bothrops jararaca
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-Leu + H2O + O2 LAAOs are flavoenzymes catalyzing the stereospecifically oxidative deamination of a wide range of L-amino acids Bothrops jararaca 4-methyl-2-oxopentanoic acid + NH3 + H2O2
-
 ?
additional information the venom enzyme from Bothrops jararaca show high antibacterial activity, e.g. against Staphylococcus aureus, via the produced H2O2, overview. The enzyme also shows hemolytic and leishmanicidal activity, overview Bothrops jararaca ?
-
 ?

Subunits

Subunits Comment Organism
? x * 38200, deglycosylated enzyme, SDS-PAGE Bothrops jararaca

Synonyms

Synonyms Comment Organism
LAAO
-
 Bothrops jararaca

Cofactor

Cofactor Comment Organism Structure
flavin a flavoenzyme Bothrops jararaca