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Literature summary for 1.4.3.4 extracted from

  • Ramsay, R.R.
    Kinetic mechanism of monoamine oxidase A (1991), Biochemistry, 30, 4624-4629.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
amphetamine
-
Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.12
-
kynuramine
-
Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
Homo sapiens 5739
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
RCH2NH2 + H2O + O2 Homo sapiens
-
RCHO + NH3 + H2O2
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Reaction

Reaction Comment Organism Reaction ID
RCH2NHR' + H2O + O2 = RCHO + R'NH2 + H2O2 mechanism Homo sapiens
RCH2NHR' + H2O + O2 = RCHO + R'NH2 + H2O2 mechanism of monoamine oxidase A Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
placenta
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine + H2O + O2
-
Homo sapiens ?
-
?
kynuramine + H2O + O2
-
Homo sapiens 3-(2-aminophenyl)-3-oxopropanal + NH3 + H2O2
-
?
RCH2NH2 + H2O + O2
-
Homo sapiens RCHO + NH3 + H2O2
-
?

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.18
-
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
-
Homo sapiens
1.9
-
kynuramine
-
Homo sapiens
5.3
-
tyramine
-
Homo sapiens