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Literature summary for 1.4.3.4 extracted from

  • Nakagawasai, O.; Arai, Y.; Satoh, S.e.; Satoh, N.; Neda, M.; Hozumi, M.; Oka, R.; Hiraga, H.; Tadano, T.
    Monoamine oxidase and head-twitch response in mice. Mechanisms of alpha-methylated substrate derivatives (2004), Neurotoxicology, 25, 223-232.
    View publication on PubMed
Search for more literature for 1.4.3.4

Inhibitors

Inhibitors Comment Organism Structure
5-fluoro-alpha-methyltryptamine a drug causing head-twitch response, IC50: 0.00018 mM Mus musculus
5-fluorotryptamine a drug causing head-twitch response, IC50: 0.00018 mM Mus musculus
6-fluoro-alpha-methyltryptamine a drug causing head-twitch response, IC50: 0.00018 mM Mus musculus
6-fluorotryptamine a drug causing head-twitch response, IC50: 0.00018 mM Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
forebrain
-
 Mus musculus
-

Synonyms

Synonyms Comment Organism
MAO-A
-
 Mus musculus
monoamine oxidase A
-
 Mus musculus

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.000032
-
 5-fluoro-alpha-methyltryptamine
-
 Mus musculus
0.0016
-
 6-fluoro-alpha-methyltryptamine
-
 Mus musculus

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.00018
-
 a drug causing head-twitch response, IC50: 0.00018 mM Mus musculus 5-fluorotryptamine
0.00018
-
 a drug causing head-twitch response, IC50: 0.00018 mM Mus musculus 6-fluorotryptamine
0.00018
-
 a drug causing head-twitch response, IC50: 0.00018 mM Mus musculus 5-fluoro-alpha-methyltryptamine
0.00018
-
 a drug causing head-twitch response, IC50: 0.00018 mM Mus musculus 6-fluoro-alpha-methyltryptamine