Application | Comment | Organism |
---|---|---|
medicine | non-selective MAO and selective MAO-A inhibitors can induce 5-hydroxytryptamine syndrome in humans when co-administered with antidepressants. Furthermore, the risk of 5-hydroxytryptamine syndrome may be lower with the selective MAO-B inhibitor selegiline | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Clorgyline | the reversible and selective MAO-A inhibitor produces increases in 5-hydroxytryptamine syndrome in the 5-hydroxytryptamine-treated rats | Rattus norvegicus | |
Pargyline | the irreversible and non-selective MAO inhibitor produces increases in 5-hydroxytryptamine syndrome in the 5-hydroxytryptamine-treated rats | Rattus norvegicus | |
selegiline | administration of the irreversible and selective MAO-B inhibitor selegiline does not produce any increase in 5-hydroxytryptamine syndrome in the 5-hydroxytryptamine-treated rats, compared with the saline control | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P21397 | - |
- |
Homo sapiens | P27338 | - |
- |
Rattus norvegicus | P19643 | - |
- |
Rattus norvegicus | P21396 | - |
- |
Synonyms | Comment | Organism |
---|---|---|
MAO-A | - |
Homo sapiens |
MAO-A | - |
Rattus norvegicus |
MAO-B | - |
Homo sapiens |
MAO-B | - |
Rattus norvegicus |
monoamine oxidase A | - |
Homo sapiens |
monoamine oxidase A | - |
Rattus norvegicus |
monoamine oxidase B | - |
Homo sapiens |
monoamine oxidase B | - |
Rattus norvegicus |