Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.4.3.4 extracted from

  • Speiser, Z.; Fine, T.; Litinetsky, L.; Eliash, S.; Blaugrund, E.; Cohen, S.
    Differential behavioral syndrome evoked in the rats after multiple doses of SSRI fluoxetine with selective MAO inhibitors rasagiline or selegiline (2008), J. Neural Transm., 115, 107-116.
    View publication on PubMed

Application

Application Comment Organism
medicine the monoamine oxidase inhibitor rasagiline may provide a much lower risk of serotonin syndrome than the monoamine oxidase inhibitor selegiline in parkinsonian patients treated with an serotonin reuptake inhibitor Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
rasagiline
-
Rattus norvegicus
selegiline
-
Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus P19643
-
-
Rattus norvegicus P21396
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
phenylethylamine + H2O + O2
-
Rattus norvegicus 2-phenylethanal + NH3 + H2O2
-
?
serotonin + H2O + O2
-
Rattus norvegicus (5-hydroxy-1H-indol-3-yl)acetaldehyde + NH3 + H2O2
-
?

Synonyms

Synonyms Comment Organism
MAO-A
-
Rattus norvegicus
MAO-B
-
Rattus norvegicus