Literature summary for 1.4.4.2 extracted from

Eisenhut, M.; Kahlon, S.; Hasse, D.; Ewald, R.; Lieman-Hurwitz, J.; Ogawa, T.; Ruth, W.; Bauwe, H.; Kaplan, A.; Hagemann, M.
The plant-like C2 glycolate cycle and the bacterial-like glycerate pathway cooperate in phosphoglycolate metabolism in cyanobacteria (2006), Plant Physiol., 142, 333-342.

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Application

Application	Comment	Organism
additional information	GDC is dispensable for cyanobacterial metabolism	Synechocystis sp.

Protein Variants

Protein Variants	Comment	Organism
additional information	inactivation of the sll0171 gene by introducing a spectinomycin-resistance cartridge	Synechocystis sp. PCC 6803
additional information	mutant affected in T-protein subunit of GDC shows similar CO2-dependent regulation as wild-type cells. Glycine decarboxylase knockout mutants exposed to low CO2 accumulate far more glycine and lysine than wild-type cells or mutants with inactivated glycerate pathway	Synechocystis sp.

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
glycine + H-protein-lipoyllysine	Synechocystis sp. PCC 6803	-	H-protein-S-aminomethyldihydrolipoyllysine + CO2	-	?

Organism

Organism	UniProt	Comment	Textmining
Synechocystis sp.	-	strain PCC 6803	-
Synechocystis sp. PCC 6803	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
glycine + H-protein-lipoyllysine	-	Synechocystis sp. PCC 6803	H-protein-S-aminomethyldihydrolipoyllysine + CO2	-	?

Subunits

Subunits	Comment	Organism
tetramer	T protein, P protein, H protein, L protein	Synechocystis sp. PCC 6803

Synonyms

Synonyms	Comment	Organism
GDC	-	Synechocystis sp.
GDC	-	Synechocystis sp. PCC 6803
Gly decarboxylase complex	-	Synechocystis sp.
glycine decarboxylase	-	Synechocystis sp.
glycine decarboxylase complex	-	Synechocystis sp. PCC 6803
glycine dehydrogenase	-	Synechocystis sp. PCC 6803
T protein	-	Synechocystis sp.

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Release 2023.1 (January 2023)