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Literature summary for 1.5.1.17 extracted from

  • Plaxton, W.C.; Storey, K.B.
    Purification and properties of alanopine dehydrogenase isozymes from the channeled whelk, Busycotypus canaliculatum (1983), Comp. Biochem. Physiol. B, 76, 321-326.
No PubMed abstract available
Search for more literature for 1.5.1.17

Inhibitors

Inhibitors Comment Organism Structure
L-Ala product inhibition Busycotypus canaliculatum
meso-Alanopine product inhibition Busycotypus canaliculatum
NAD+ product inhibition Busycotypus canaliculatum
pyruvate product inhibition Busycotypus canaliculatum

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
additional information
-
 additional information Km-values for the 3 isoenzymes at pH 6.5 and at pH 7.5 Busycotypus canaliculatum

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Busycotypus canaliculatum the enzyme from hepatopancreas is involved in alanopine oxidation ?
-
 ?
additional information Busycotypus canaliculatum muscle enzyme is involved in anaerobic glycolysis ?
-
 ?

Organism

Organism UniProt Comment Textmining
Busycotypus canaliculatum
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Busycotypus canaliculatum

Source Tissue

Source Tissue Comment Organism Textmining
foot muscle
-
 Busycotypus canaliculatum
-
gill
-
 Busycotypus canaliculatum
-
hepatopancreas
-
 Busycotypus canaliculatum
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-Ala + pyruvate + NADH
-
 Busycotypus canaliculatum 2,2'-Iminodipropanoate + NAD+ + H2O
-
 ?
additional information the enzyme from hepatopancreas is involved in alanopine oxidation Busycotypus canaliculatum ?
-
 ?
additional information muscle enzyme is involved in anaerobic glycolysis Busycotypus canaliculatum ?
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.5
-
 with 35 mM L-Ala and 1.4 mM pyruvate as substrate, foot muscle enzyme Busycotypus canaliculatum
7.1
-
 with 50 mM L-Ala and 2 mM pyruvate as substrates, foot muscle enzyme Busycotypus canaliculatum
8.1
-
 with 15 mM meso-alanopine and 1.2 mM NAD+ as substrates, enzyme from hepatopancreas Busycotypus canaliculatum
8.5
-
 with 15 mM meso-alanopine and 1.2 mM NAD+ as substrates, foot muscle enzyme Busycotypus canaliculatum
8.6
-
 with 15 mM meso-alanopine and 1.2 mM NAD+ as substrates, enzyme from gill Busycotypus canaliculatum
9
-
 with 40 mM meso-alanopine and 2 mM NAD+ as substrates, all three isoenzymes Busycotypus canaliculatum

Cofactor

Cofactor Comment Organism Structure
NAD+
-
 Busycotypus canaliculatum
NADH
-
 Busycotypus canaliculatum