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Literature summary for 1.5.1.3 extracted from
- Understanding the role of Leu22 variants in methotrexate resistance: comparison of wild-type and Leu22Arg variant mouse and human dihydrofolate reductase ternary crystal complexes with methotrexate and NADPH (2005), Acta crystallogr. Sect. D, 61, 147-155.
Crystallization (Commentary)
| Crystallization (Comment) | Organism |
|---|---|
| wild-type and mutant L22R in ternary complex with methotrexate and NADPH, comparison with human anologues. Active site of mouse enzyme is larger than that of human enzyme | Mus musculus |
| wild-type and mutant L22R in ternary complex with methotrexate and NADPH, comparison with mouse anologues. Active site of mouse enzyme is larger than that of human enzyme | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
| Mus musculus | - |
- |
- |
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