Literature summary for 1.5.1.3 extracted from

Fogel, G.B.; Cheung, M.; Pittman, E.; Hecht, D.
In silico screening against wild-type and mutant Plasmodium falciparum dihydrofolate reductase (2008), J. Mol. Graph. Model., 26, 1145-1152.

Search for more literature for 1.5.1.3

Application

Application	Comment	Organism
drug development	modeling of 31 pyrimethamine derivatives into the active site of dihydrofolate reductase obtained from crystal structures 1J3I.pdb and 1J3K.pdb. Evaluation of predicted binding modes and key protein-ligand interactions	Plasmodium falciparum

Crystallization (Commentary)

Crystallization (Comment)	Organism
modeling of 31 pyrimethamine derivatives into the active site of dihydrofolate reductase obtained from crystal structures 1J3I.pdb and 1J3K.pdb. Evaluation of predicted binding modes and key protein-ligand interactions	Plasmodium falciparum

Organism

Organism	UniProt	Comment	Textmining
Plasmodium falciparum	P13922	-	-

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Release 2023.1 (January 2023)