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Literature summary for 1.5.1.3 extracted from

  • Wu, S.C.; Hong, W.W.; Liu, J.H.
    Short hairpin RNA targeted to dihydrofolate reductase enhances the immunoglobulin G expression in gene-amplified stable Chinese hamster ovary cells (2008), Vaccine, 26, 4969-4974.
    View publication on PubMed

Application

Application Comment Organism
synthesis the use of the dihydrofolate-reductase-targeted short hairpin RNA vector can enhance the IgG expression in the gene-amplified stable CHO cells and uphold the IgG expression in methotrexate-free cultures Cricetulus griseus

Protein Variants

Protein Variants Comment Organism
additional information use of the dihydrofolate reductase-targeted short hairpin RNA vector for immunoglobulin G expression in geneamplified stable CHO cells. Cells increase IgG expression at 1.0 microM methotrexate by more than 100% and improve the genomic stability of IgG expression in methotrexate-free cultures by approximately 30% Cricetulus griseus

Organism

Organism UniProt Comment Textmining
Cricetulus griseus
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Source Tissue

Source Tissue Comment Organism Textmining