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Literature summary for 1.5.1.34 extracted from
- Inactivation of dihydropteridine reductase (human brain) by platinum(II) complexes (1987), Eur. J. Biochem., 164, 403-409.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| cis-Diaminodichloroplatinum | - |
Homo sapiens |  |
| K2PtCl4 | 0.208 mM, half-life of inactivation: 3.1 min, NADH and 2 mM dithiothreitol completely protect | Homo sapiens | |
| trans-Diaminodichloroplatinum | - |
Homo sapiens | |
| trans-Pt(NH3)Cl2 | 1 mM, 96% inactivation after 2 h | Homo sapiens | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Homo sapiens | - |
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Release 2023.1 (January 2023)
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