Inhibitors | Comment | Organism | Structure |
---|---|---|---|
aminopterin | no inhibition up to 0.1 mM | Bos taurus | |
methotrexate | no inhibition up to 0.1 mM | Bos taurus | |
additional information | enzyme from adrenal medulla, not inhibited by aminopterin and methotrexate | Bos taurus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
quinonoid 7,8-(6H)-dihydrobiopterin + NAD(P)H | Bos taurus | may also have an important role in regulation of catecholamine synthesis | 5,6,7,8-tetrahydrobiopterin + NAD(P)+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
adrenal medulla | - |
Bos taurus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
quinonoid 6,7-dimethyl-7,8-(6H)-dihydropterin + NAD(P)H | enzyme from adrenal medulla | Bos taurus | 6,7-dimethyl-5,6,7,8-tetrahydropterin + NAD(P)+ | - |
? | |
quinonoid 7,8-(6H)-dihydrobiopterin + NAD(P)H | may also have an important role in regulation of catecholamine synthesis | Bos taurus | 5,6,7,8-tetrahydrobiopterin + NAD(P)+ | - |
? |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
80 | - |
1 min, inactivation | Bos taurus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADH | utilizes both NADH and NADPH | Bos taurus | |
NADPH | utilizes both NADH and NADPH | Bos taurus |