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Literature summary for 1.5.1.44 extracted from

  • Matuschek, M.; Wallwey, C.; Xie, X.; Li, S.M.
    New insights into ergot alkaloid biosynthesis in Claviceps purpurea: an agroclavine synthase EasG catalyses, via a non-enzymatic adduct with reduced glutathione, the conversion of chanoclavine-I aldehyde to agroclavine (2011), Org. Biomol. Chem., 9, 4328-4335.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Aspergillus fumigatus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
chanoclavine-I aldehyde + NADH + H+ this reaction occurs in the presence of the old yellow enzyme FgaOx3. Together with GSH and NADPH, the enzyme also catalyses the conversion of chanoclavine-I aldehyde to agroclavine in the absence of the old yellow enzyme FgaOx3 Aspergillus fumigatus festuclavine + NAD+
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Synonyms

Synonyms Comment Organism
festuclavine synthase
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Aspergillus fumigatus
FgaFS
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Aspergillus fumigatus