Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.5.8.2 extracted from

  • Barber, M.J.; Pollock, V.; Spence, J.T.
    Microcoulometric analysis of trimethylamine dehydrogenase (1988), Biochem. J., 256, 657-659.
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
phenylhydrazine lowers the requirement of reducing equivalents from three to 0.9 Methylophilus methylotrophus

Metals/Ions

Metals/Ions Comment Organism Structure
Fe 4Fe-4S-center Methylophilus methylotrophus

Organism

Organism UniProt Comment Textmining
Methylophilus methylotrophus
-
-
-
Methylophilus methylotrophus W3A1
-
-
-

Purification (Commentary)

Purification (Comment) Organism
to homogeneity, chromatography steps Methylophilus methylotrophus

Source Tissue

Source Tissue Comment Organism Textmining
cell culture
-
Methylophilus methylotrophus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.1
-
-
Methylophilus methylotrophus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
trimethylamine + H2O + phenazine methosulfate requires the addition of 3 reducing equivalents per subunit for complete reduction Methylophilus methylotrophus dimethylamine + formaldehyde + reduced phenazine methosulfate
-
?
trimethylamine + H2O + phenazine methosulfate requires the addition of 3 reducing equivalents per subunit for complete reduction Methylophilus methylotrophus W3A1 dimethylamine + formaldehyde + reduced phenazine methosulfate
-
?

Cofactor

Cofactor Comment Organism Structure
FMN
-
Methylophilus methylotrophus