Application | Comment | Organism |
---|---|---|
medicine | sarcosine dehydrogenase is defective in patient with sarcosinemia | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
- |
Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
99505 | - |
1 * 99505 | Homo sapiens |
99510 | - |
including covalently bound FAD | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
sarcosine + acceptor + H2O | Homo sapiens | acceptors: 2,6-dichlorophenolindophenol, phenazine methosulfate | glycine + formaldehyde + reduced acceptor | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
kidney | adult and fetal | Homo sapiens | - |
liver | adult and fetal | Homo sapiens | - |
pancreas | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
sarcosine + acceptor + H2O | acceptors: 2,6-dichlorophenolindophenol, phenazine methosulfate | Homo sapiens | glycine + formaldehyde + reduced acceptor | - |
? |
Subunits | Comment | Organism |
---|---|---|
monomer | 1 * 99505 | Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
FAD | covalent bound FAD linked via 8a-position of the isoalloxazin ring to the imidazole N(3) of a histidine residue, structural homology between the amino acid sequence of the flavin-peptides | Homo sapiens | |
tetrahydrofolate | - |
Homo sapiens |