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Literature summary for 1.6.1.2 extracted from
- Resolution and reconstitution of Rhodospirillum rubrum pyridine dinucleotide transhydrogenase: chemical modification with N-ethylmaleimide and 2,4-pentanedione (1979), Biochemistry, 18, 4315-4322.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| N-ethylmaleimide | inactivation of integral membrane bound component and soluble protein factor of enzyme from chromatophore, NADPH potentiates inactivation of the enzyme complex at low concentrations, NADP+ partially protects the intact complex and fully protects both components | Rhodospirillum rubrum |  |
| Pentane-2,4-dione | inactivation of chromatophore complex, 156 mM, approx. 85% inactivation after 30 min, NADPH and NADP+ partially protect, half-maximal protection with 0.015 mM NADPH and 0.030 mM NADP+ respetively | Rhodospirillum rubrum | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rhodospirillum rubrum | - |
- |
- |
Renatured (Commentary)
| Renatured (Comment) | Organism |
|---|---|
| reconstitution into liposomes | Rhodospirillum rubrum |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NAD+ | - |
Rhodospirillum rubrum | |
| NADH | - |
Rhodospirillum rubrum | |
| NADP+ | - |
Rhodospirillum rubrum | |
| NADPH | - |
Rhodospirillum rubrum | |
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