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Literature summary for 1.6.1.2 extracted from

  • Peake, S.J.; Venning, J.D.; Jackson, J.B.
    A catalytically active complex formed from the recombinant dI protein of Rhodospirillum rubrum transhydrogenase, and the recombinant dIII protein of the human enzyme (1999), Biochim. Biophys. Acta, 1411, 159-169.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expression of domain I in Escherichia coli Rhodospirillum rubrum
expresssion of domain III in Escherichia coli Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrial membrane
-
Homo sapiens 31966
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Rhodospirillum rubrum
-
-
-

Purification (Commentary)

Purification (Comment) Organism
recombinant domain I Rhodospirillum rubrum
recombinant domain III Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
NADH + NADP+ reaction is catalyzed by a mixture of recombinant human domain III and recombinant R. rubrum domain I Homo sapiens NAD+ + NADPH
-
r
NADH + NADP+ reaction is catalyzed by a mixture of recombinant human domain III and recombinant R. rubrum domain I Rhodospirillum rubrum NAD+ + NADPH
-
r

Cofactor

Cofactor Comment Organism Structure
NAD+
-
Homo sapiens
NAD+
-
Rhodospirillum rubrum
NADH
-
Homo sapiens
NADH
-
Rhodospirillum rubrum
NADP+
-
Homo sapiens
NADP+
-
Rhodospirillum rubrum
NADPH
-
Homo sapiens
NADPH
-
Rhodospirillum rubrum