Crystallization (Comment) | Organism |
---|---|
dI2dIII1 complex and dI domain | Rhodospirillum rubrum |
dIII domain | Homo sapiens |
dIII domain | Bos taurus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Dicyclohexylcarbodiimide | complete inhibition if 0.5 mol are bound to 1 mol of enzyme | Bos taurus | |
fluorosulfonyl-para-benzyladenosine | complete inhibition if 0.5 mol are bound to 1 mol of enzyme | Bos taurus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Escherichia coli | 16020 | - |
membrane | - |
Homo sapiens | 16020 | - |
membrane | - |
Bos taurus | 16020 | - |
membrane | - |
Entamoeba histolytica | 16020 | - |
membrane | - |
Rhodospirillum rubrum | 16020 | - |
mitosome | - |
Entamoeba histolytica | 32047 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
NADH + NADP+ | Escherichia coli | links hydride transfer between NAD(H) and NADP(H) to the translocation of protons across membrane, hydride ion equivalent is transferred from the A side of NC4 of NADH to the B side of NC4 of NADP+, provides NADPH for metabolic biosynthesis and reduction of glutathione | NAD+ + NADPH | - |
r | |
NADH + NADP+ | Homo sapiens | links hydride transfer between NAD(H) and NADP(H) to the translocation of protons across membrane, hydride ion equivalent is transferred from the A side of NC4 of NADH to the B side of NC4 of NADP+, provides NADPH for metabolic biosynthesis and reduction of glutathione | NAD+ + NADPH | - |
r | |
NADH + NADP+ | Bos taurus | links hydride transfer between NAD(H) and NADP(H) to the translocation of protons across membrane, hydride ion equivalent is transferred from the A side of NC4 of NADH to the B side of NC4 of NADP+, provides NADPH for metabolic biosynthesis and reduction of glutathione | NAD+ + NADPH | - |
r | |
NADH + NADP+ | Entamoeba histolytica | links hydride transfer between NAD(H) and NADP(H) to the translocation of protons across membrane, hydride ion equivalent is transferred from the A side of NC4 of NADH to the B side of NC4 of NADP+, provides NADPH for metabolic biosynthesis and reduction of glutathione | NAD+ + NADPH | - |
r | |
NADH + NADP+ | Rhodospirillum rubrum | links hydride transfer between NAD(H) and NADP(H) to the translocation of protons across membrane, hydride ion equivalent is transferred from the A side of NC4 of NADH to the B side of NC4 of NADP+, provides NADPH for metabolic biosynthesis and reduction of glutathione | NAD+ + NADPH | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Entamoeba histolytica | - |
- |
- |
Escherichia coli | - |
- |
- |
Homo sapiens | - |
- |
- |
Rhodospirillum rubrum | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
NADH + NADP+ | - |
Escherichia coli | NAD+ + NADPH | - |
r | |
NADH + NADP+ | - |
Homo sapiens | NAD+ + NADPH | - |
r | |
NADH + NADP+ | - |
Bos taurus | NAD+ + NADPH | - |
r | |
NADH + NADP+ | - |
Entamoeba histolytica | NAD+ + NADPH | - |
r | |
NADH + NADP+ | - |
Rhodospirillum rubrum | NAD+ + NADPH | - |
r | |
NADH + NADP+ | links hydride transfer between NAD(H) and NADP(H) to the translocation of protons across membrane, hydride ion equivalent is transferred from the A side of NC4 of NADH to the B side of NC4 of NADP+, provides NADPH for metabolic biosynthesis and reduction of glutathione | Escherichia coli | NAD+ + NADPH | - |
r | |
NADH + NADP+ | links hydride transfer between NAD(H) and NADP(H) to the translocation of protons across membrane, hydride ion equivalent is transferred from the A side of NC4 of NADH to the B side of NC4 of NADP+, provides NADPH for metabolic biosynthesis and reduction of glutathione | Homo sapiens | NAD+ + NADPH | - |
r | |
NADH + NADP+ | links hydride transfer between NAD(H) and NADP(H) to the translocation of protons across membrane, hydride ion equivalent is transferred from the A side of NC4 of NADH to the B side of NC4 of NADP+, provides NADPH for metabolic biosynthesis and reduction of glutathione | Bos taurus | NAD+ + NADPH | - |
r | |
NADH + NADP+ | links hydride transfer between NAD(H) and NADP(H) to the translocation of protons across membrane, hydride ion equivalent is transferred from the A side of NC4 of NADH to the B side of NC4 of NADP+, provides NADPH for metabolic biosynthesis and reduction of glutathione | Entamoeba histolytica | NAD+ + NADPH | - |
r | |
NADH + NADP+ | links hydride transfer between NAD(H) and NADP(H) to the translocation of protons across membrane, hydride ion equivalent is transferred from the A side of NC4 of NADH to the B side of NC4 of NADP+, provides NADPH for metabolic biosynthesis and reduction of glutathione | Rhodospirillum rubrum | NAD+ + NADPH | - |
r |
Subunits | Comment | Organism |
---|---|---|
dimer | monomer is split into PntA and PntB chain, enzyme displays an overall dimeric structure | Escherichia coli |
dimer | monomer is split into PntAA, PntAB, and PntB chain, enzyme displays an overall dimeric structure, dI dimers are formed in solutions of isolated dI domains | Rhodospirillum rubrum |
monomer | solution of isolated dIII domains | Rhodospirillum rubrum |
trimer | trimers of dI2dIII1 are formes in mixed solutions containing dI and dIII domains | Rhodospirillum rubrum |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD(P)+ | - |
Escherichia coli | |
NAD(P)+ | - |
Homo sapiens | |
NAD(P)+ | - |
Bos taurus | |
NAD(P)+ | - |
Entamoeba histolytica | |
NAD(P)+ | - |
Rhodospirillum rubrum | |
NAD(P)H | - |
Escherichia coli | |
NAD(P)H | - |
Homo sapiens | |
NAD(P)H | - |
Bos taurus | |
NAD(P)H | - |
Entamoeba histolytica | |
NAD(P)H | - |
Rhodospirillum rubrum |