Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Rattus norvegicus | - |
- |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Rattus norvegicus | detoxification of drugs, inactivation of procarcinogens | ? | - |
? | |
additional information | Rattus norvegicus | monooxygenase system composed of cytochrome P-450, NADPH-cytochrome c reductase, phospholipids | ? | - |
? | |
additional information | Rattus norvegicus Sprague-Dawley | detoxification of drugs, inactivation of procarcinogens | ? | - |
? | |
additional information | Rattus norvegicus Sprague-Dawley | monooxygenase system composed of cytochrome P-450, NADPH-cytochrome c reductase, phospholipids | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
Sprague-Dawley strain | - |
Rattus norvegicus Sprague-Dawley | - |
Sprague-Dawley strain | - |
Purification (Comment) | Organism |
---|---|
single-step procedure involving affinity chromatography on agarose-hexane-adenosine 2',5'-diphosphate or two-column procedure involving chromatography on n-octylamino-Sepharose 4B followed by chromatography on 2',5'-ADP | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | phenobarbital-treated animals | Rattus norvegicus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
62.5 | - |
purification by affinity chromatography on agarose-hexane-adenosine 2',5'-diphosphate | Rattus norvegicus |
63.8 | - |
purification by n-octylamino-Sepharose 4B and 2',5'-ADP column chromatography | Rattus norvegicus |
Storage Stability | Organism |
---|---|
-78°C, 30 mM potassium phosphate buffer, pH 7.7, 0.1 mM EDTA, 20% glycerol, 0.4 mM PMSF | Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | detoxification of drugs, inactivation of procarcinogens | Rattus norvegicus | ? | - |
? | |
additional information | monooxygenase system composed of cytochrome P-450, NADPH-cytochrome c reductase, phospholipids | Rattus norvegicus | ? | - |
? | |
additional information | detoxification of drugs, inactivation of procarcinogens | Rattus norvegicus Sprague-Dawley | ? | - |
? | |
additional information | monooxygenase system composed of cytochrome P-450, NADPH-cytochrome c reductase, phospholipids | Rattus norvegicus Sprague-Dawley | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 75000-76000, SDS-PAGE | Rattus norvegicus |