Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.6.2.4 extracted from

  • Feidt, D.M.; Klein, K.; Nuessler, A.; Zanger, U.M.
    RNA-interference approach to study functions of NADPH: cytochrome P450 oxidoreductase in human hepatocytes (2009), Chem. Biodivers., 6, 2084-2091.
    View publication on PubMed
Search for more literature for 1.6.2.4

Localization

Localization Comment Organism GeneOntology No. Textmining

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
78000
-
 SDS-PAGE Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2 ferricytochrome P450 + NADPH Homo sapiens
-
 2 ferrocytochrome P450 + NADP+ + H+
-
 ?
additional information Homo sapiens the enzyme donates electrons derived from NADPH to a variety of acceptor proteins, including squalene monooxygenase, 7-dehydro-cholesterol reductase, heme oxygenase, cytochrome b5 , and many microsomal cytochromes P450 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
Hep-G2 cell
-
 Homo sapiens
-
hepatocyte
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2 ferricytochrome c + NADPH
-
 Homo sapiens 2 ferrocytochrome c + NADP+ + H+
-
 ?
2 ferricytochrome P450 + NADPH
-
 Homo sapiens 2 ferrocytochrome P450 + NADP+ + H+
-
 ?
additional information the enzyme donates electrons derived from NADPH to a variety of acceptor proteins, including squalene monooxygenase, 7-dehydro-cholesterol reductase, heme oxygenase, cytochrome b5 , and many microsomal cytochromes P450 Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
NADPH: cytochrome P450 oxidoreductase
-
 Homo sapiens
POR
-
 Homo sapiens

Cofactor

Cofactor Comment Organism Structure
FAD
-
 Homo sapiens
FMN
-
 Homo sapiens
NADPH
-
 Homo sapiens