Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | the membrane-bound NADPH oxidase in phagocytes, gp91phox/Nox2, produces superoxide, a precursor of microbicidal oxidants, thereby playing a crucial role in host defense. Activation of gp91phox/Nox2 requires assembly with the cytosolic proteins p67phox and p47phox, each containing two SH3 domains. p67phox-SH3(N) specifically functions in gp91phox/Nox2 activation probably via facilitating oxidase assembly | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | the membrane-bound NADPH oxidase in phagocytes, gp91phox/Nox2, produces superoxide, a precursor of microbicidal oxidants, thereby playing a crucial role in host defense. Activation of gp91phox/Nox2 requires assembly with the cytosolic proteins p67phox and p47phox, each containing two SH3 domains. p67phox-SH3(N) specifically functions in gp91phox/Nox2 activation probably via facilitating oxidase assembly | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
gp91phox/Nox2 | - |
Homo sapiens |