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Literature summary for 1.6.3.1 extracted from

  • Feillet-Coudray, C.; Sutra, T.; Fouret, G.; Ramos, J.; Wrutniak-Cabello, C.; Cabello, G.; Cristol, J.P.; Coudray, C.
    Oxidative stress in rats fed a high-fat high-sucrose diet and preventive effect of polyphenols: Involvement of mitochondrial and NAD(P)H oxidase systems (2009), Free Radic. Biol. Med., 46, 624-632.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
diphenyleneiodonium
-
Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
gastrocnemius
-
Rattus norvegicus
-
heart left ventricle Rattus norvegicus
-
liver
-
Rattus norvegicus
-
skeletal muscle
-
Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
NADPH + H+ + O2
-
Rattus norvegicus NADP+ + H2O2
-
?

Synonyms

Synonyms Comment Organism
NAPDH oxidase
-
Rattus norvegicus

Expression

Organism Comment Expression
Rattus norvegicus NADPH oxidase expression (p22phox and p47phox) and NADPH oxidase-dependent superoxide anion production are not modified in 12 week high-fat highsucrose diet-fed rats additional information

General Information

General Information Comment Organism
physiological function in skeletal muscle and in heart the NADPH oxidase system is mainly involved in oxidative stress Rattus norvegicus