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Literature summary for 1.6.3.1 extracted from

  • Gupte, S.; Labinskyy, N.; Gupte, R.; Csiszar, A.; Ungvari, Z.; Edwards, J.G.
    Role of NAD(P)H oxidase in superoxide generation and endothelial dysfunction in Goto-Kakizaki (GK) rats as a model of nonobese NIDDM (2010), PLoS ONE, 5, e11800.
    View publication on PubMedView publication on EuropePMC
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Inhibitors

Inhibitors Comment Organism Structure
apocynin specific Nox inhibitor Rattus norvegicus
diphenyleneiodonium
-
 Rattus norvegicus
pg91ds-tat
-
 Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Rattus norvegicus 16020
-

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
aorta
-
 Rattus norvegicus
-

Synonyms

Synonyms Comment Organism
NADPH oxidase
-
 Rattus norvegicus
NOX
-
 Rattus norvegicus

Expression

Organism Comment Expression
Rattus norvegicus hyperglycemia induces increases in NAD(P)H oxidase activity up

General Information

General Information Comment Organism
physiological function NAD(P)H derived superoxide generation is the underlying cause of vasoactive dysfunction in hyperglycemic Goto-Kakizaki arteries Rattus norvegicus