Application | Comment | Organism |
---|---|---|
medicine | plasma concentration of renalase is markedly reduced in patients with end-stage renal disease, as compared with healthy subjects | Homo sapiens |
medicine | renalase infusion in rats causes a decrease in cardiac contractility, heart rate, and blood pressure and prevents a compensatory increase in peripheral vascular tone | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q5VYX0 | - |
- |
Rattus norvegicus | Q5U2W9 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
blood | enzyme is secreted into the blood by the kidney | Homo sapiens | - |
heart | besides kidney, renalase gene expression is detectable in the heart, skeletal muscle, and the small intestine | Homo sapiens | - |
kidney | enzyme is secreted into the blood by the kidney. Gene expression is highest in the kidney | Homo sapiens | - |
skeletal muscle | besides kidney, renalase gene expression is detectable in the heart, skeletal muscle, and the small intestine | Homo sapiens | - |
small intestine | besides kidney, renalase gene expression is detectable in the heart, skeletal muscle, and the small intestine | Homo sapiens | - |