Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | heating at 42°C for 1 h significantly increases the expression of NQO1 in cancer cells | Mus musculus | |
additional information | heating at 42°C for 1 h significantly increases the expression of NQO1 in cancer cells | Homo sapiens |
Application | Comment | Organism |
---|---|---|
drug development | mild temperature heat shock elevates the NQO1 expression in cancer cells, which in turn markedly increases the sensitivity of the cells to the bioreductive drug beta-lapachone in vitro and in vivo | Mus musculus |
drug development | mild temperature heat shock elevates the NQO1 expression in cancer cells, which in turn markedly increases the sensitivity of the cells to the bioreductive drug beta-lapachone in vitro and in vivo | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Mus musculus | - |
C3H mice | - |
Mus musculus C3H | - |
C3H mice | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
A-549 cell | - |
Homo sapiens | - |
fibrosarcoma cell | - |
Mus musculus | - |
lung cancer cell | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
NAD(P)H: Quinone oxidoreductase | - |
Mus musculus |
NAD(P)H: Quinone oxidoreductase | - |
Homo sapiens |
NQO1 | - |
Mus musculus |
NQO1 | - |
Homo sapiens |